Aim: This study investigates the frequency of and factors determining sharps injuries among health-care workers in Gülhane Military Medical Academy (GMMA). Material and Methods: We conducted the research from January to May 2005 at the clinics of the Department of Surgical Clinical Sciences of 1200-bed hospital of GMMA. There are 273 doctors, 315 nurses and 92 technicians serving at the Department of Surgical Clinical Sciences. All doctors and nurses serving at the surgical clinics, without exception, are included in the research. The sample universe of the research includes 341 employees of 128 doctors, 159 nurses and 54 technicians who accepted to answer the survey. We apply arithmetic mean and frequency analyses to the data and chi-square tests for the group comparisons. Results: According to the evaluation of the data from the research; 305 healthcare workers (n=341) claimed that they were injured with sharps at least once during their occupational experience. It was found that while physicians and technicians were most injured in operating rooms, nurses were most injured in intensive care units. While physicians were injured most with suture needle while suturing, nurses and technicians were most injured with the syringe needle. Conclusion: Considering the survey findings, we suggest that, units must be established in hospitals to guide health care workers against sharps injuries, protect them from pathogens caused by blood and make record of incidents.