BLOOD PRESSURE CONTROL AND NONDIPPING IN HYPERTENSIVE PATIENTS WITH MILD RENAL DYSFUNCTION
Mustafa APARCI, Ejder KARDEŞOĞLU, Zafer IŞILAK, Ömer YİĞİNER, Ömer UZ, Cem DEMİRBOLAT, Namık ÖZMEN, Bekir Yılmaz CİNGÖZBAY, Alper UÇAK, Bekir Sıtkı CEBECİ
Özet
Aim: Renal dysfunction is one of the end organ damages induced by hypertension. We aimed to evaluate the blood pressure control and dipping status in hypertensive patients with mild renal dysfunction. Material and Method: Sixty seven patients (57.4±11.9, 19 male, 48 female) were performed 24 hour ambulatory blood pressure monitoring. Renal functions were defined as glomerular filtration rate (GFR) estimated by MDRD Formula. Patients with diabetes and/or coronary artery disease were excluded. Averages of 24 hour, daytime and nighttime systolic and diastolic blood pressures and also dipping status of patients were compared between the groups with GFR under and above 60 ml/min. Statistical analysis were performed by Independent Samples t test using SPSS 11.0. Results: 24 hour, daytime and nighttime systolic and diastolic blood pressures were higher in hypertensive patients with GFR lower than 60 ml/min (p>0.05, Table 1). Distribution of dipping status was not different between groups (Table 2). However predominance of nondipping status in both groups was an alerting finding. Conclusion: Blood pressure control is particularly important in hypertensive patients with GFR <60 ml/min to slow the course of renal dysfunction. Predominance of nondipping should be overcomed by effective antihypertensive management.
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